4 December 2025

December 4: Webinar on human metabolism: combination of in vitro and in silico models

The Swedish 3Rs Center invites you to the webinar on combination of organ-on-a-chip and computational models to study metabolism and to predict drug effects in humans. The webinar is a part of webinar series with a focus on Replace: a shift towards more human-based models for better research and drug discovery.

The webinar will be held on Thursday, December 4 at 12.00–13.00 CET.

Illustration of human metabolism model created by the Swedish 3Rs Center.

We are pleased to welcome an outstanding collaboration between two researchers with backgrounds in industry and in academia who will share insights from their work on organ(s)-on-a-chip models in combination with computational models for the purpose of predicting clinical outcomes in drug development. Special focus is on liver–pancreas-on-a-chip model and predictive computational modelling.

Liisa Vilén – is a Director of Microphysiological Systems team at AstraZeneca. Her team uses organ-on-a-chip (OoC) technology to study cardiovascular, renal, and metabolic diseases and to advance the development of future treatments.

Oscar Silfvergren – is an industrial doctoral student at SUND sound medical decisions and the Department of Biomedical Engineering at the Linköping University. His work is focused on developing computational models to understand organ-on-a-chip metabolism and translate that metabolism to humans.

After the presentations, there will be time for questions from the audience.

Who should attend?

The webinar is directed towards academia with a focus on early career researchers, postdoctoral/doctoral students, researchers in respective fields, as well as industry and stakeholders interested in new assessment methodologies (NAMs) and in the 3Rs.

National network

The Swedish 3Rs Center maintains a national network for researchers and government agencies with interest in animal-free methods for research, toxicity screening and/or for regulatory purposes. The network should facilitate contact and exchange of information between researchers and government agencies. When registering for the seminar you will also have the opportunity to join the network.

Time and place

Date: December 4
Time: 12.00–13.00 CET
Place: Zoom, those who register will receive the Zoom link via email the day before the webinar.

Registration

Please fill out the form to register. Registration closes on December 3.

You should receive an email when you have registered

When you have sent your registration, you will automatically receive an email that confirms your registration. Should you not receive such an email, you need to make a new registration.

Mail name e-mail:

Last day for registrations
2025-12-03

Name * (mandatory)

E-mail * (mandatory)

Do you need a certificate of attendance? * (mandatory)

Do you need a certificate of attendance?

Yes
No

To be eligible for a certificate of attendance, you must attend at least 50 minutes of the webinar. Make sure to use the same name in Zoom as in your registration, so that we can identify you in the attendance list.

Would you like to join the Replace-network maintained by the Swedish 3Rs Center?

Yes, I would like to join the network and receive information from the Swedish 3Rs Center.
Yes, I would like to join the network and receive information from the Swedish 3Rs Center. In addition the Swedish 3Rs Center may share my contact details with relevant non-commercial partners and/or authorities within the network, in order to facilitate communication and exchange of information.
I am already part of the network.
No, I do not want to join the network.

Consent to handle personal data

To register to the other webinars in Replace series please use the link below.

Replace webinar series

Senast uppdaterad: 2025-10-23